January 2020

WITec Consolidates Sales, Applications and Technical Support for French Market

WITec GmbH, industry-leading manufacturer of 3D confocal Raman imaging and correlative microscopy systems, has updated its organizational structure in France to streamline communication and better leverage in-house technical expertise.

Dr. Maxime Tchaya, a longtime member of the WITec team, will manage the French market directly. His responsibilities include all sales activities and the coordination of technical support, equipment demonstrations and sample measurements.

Dr. Tchaya is native French speaker who began with WITec as an applications scientist before bringing his thorough, practical knowledge of WITec microscopes to the sales department. This experience will enable him to precisely address the requirements of the local client base while providing them with a direct conduit to WITec’s research and development group.

WITec renforce son service commercial et technique sur le marché français

WITec GmbH, leader de la microscopie confocale Raman 3D et fabriquant de plateformes de microscopie corrélative, renforce son organisation en France.

Dr. Maxime Tchaya, membre de longue date de l'équipe WITec, prend la responsabilité de la commercialisation et du support des solutions WITec en France. 

Sa longue expérience au sein de l’équipe d’application, et son excellente connaissance du marché français, sont autant d’atouts qui lui permettront de répondre avec précision et efficacité aux besoins de la clientèle, tout en la rapprochant davantage de l’équipe R&D pour les demandes spécifiques.


Dr. Maxime Tchaya
Area Manager France - Canada - Poland
Lise-Meitner-Str. 6
89081 Ulm, Germany
Tel: +49 (0) 731 140700





Dr. Maxime Tchaya. New Area Manager France, Canada and Poland

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December 2019

WITec ParticleScout Wins Innovation Award from The Analytical Scientist

ParticleScout, WITec’s advanced tool for microparticle analysis, has been recognized by The Analytical Scientist Innovation Awards (TASIAs) as one of the most inventive scientific products of 2019. This distinction has been bestowed at a time when microparticles generally, and microplastics more specifically, are receiving widespread attention in media.

The Analytical Scientist is a print and online journal that covers the latest developments in measurement science. The goal of the TASIAs, which are determined by a panel of experts, is “To highlight the latest and greatest technology, instrumentation and software making waves throughout the analytical science community.”

ParticleScout is a powerful software component available for the alpha300 Raman microscope series that enables researchers to find, classify, quantify and identify particles with unprecedented speed and ease of use. It provides a greatly accelerated workflow while making full use of confocal Raman microscopy’s capabilities for label-free and nondestructive chemical characterization. ParticleScout delivers thorough and detailed insight to the researcher in microplastics research, environmental science, pharmaceutical research, geology, food science and many other fields.

“We’re thrilled that ParticleScout has received an Innovation Award from The Analytical Scientist,” says Joachim Koenen, co-founder and managing director of WITec. “The TASIAs acknowledge original, useful technologies that reflect research at this very moment, and there are few current topics in science that concern the public as much as microparticles.”  

This is the second time that WITec has been among the winners of the award, having been previously honored for RISE (Raman Imaging and Scanning Electron) Microscopy.


The Analytical Scientist Innovation Awards 2019 Page:

WITec ParticleScout Page:


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November 2019

Specialized Microscope Configurations in China

One of the unique advantages of the WITec alpha300 confocal microscope series is its modularity. Customers can configure systems to meet the specific requirements of their research, and even reconfigure them as their experiments evolve. This flexibility combined with the components' inherent stability also allows integration with many other laboratory devices, such as environmental enclosures and sample stages.

WITec Product Manager Dr. Tom Dieing recently traveled through China and met with groups operating specialized WITec microscopes that show how alpha300 series modules can be assembled to create the perfect tool for a particular job.

At Fudan University – Shanghai Institute of Intelligent Electronics and Systems, a system based on the alpha300 R was modified to investigate heterostructures of graphene and tungsten disulfide. It allows high resolution confocal Raman imaging measurements ranging from <8K up to 500K inside a cryogenic cell that is fully integrated onto the alpha300 R motorized stage. It also features three excitation lasers in 532, 633 and 785 nanometers with full polarization control for the analysis of temperature- and polarization state-dependent Raman and photoluminescence signals.

Fudan University – Laboratory of Advanced Materials configured an instrument for research on black phosphorus and high temperature superconducting materials that uses an alpha300 R located within a sealed Argon-filled glove box. This allows samples produced with molecular beam epitaxy (MBE) or chemical vapor deposition (CVD) to be brought directly onto the microscope stage without exposing them to air. The small footprint and fiber-based excitation and detection paths integral to all WITec microscopes enable the electronics, lasers and spectrometer to be placed directly under the enclosure. This instrument also includes the remotely-operated TrueComfort option for automated white light/Raman switching and TruePower for precise, repeatable laser power determination.

At the Department of Modern Optics at Nanjing University there is a 488nm laser for Raman and PL measurements, a current-sensing module and a 1064nm picosecond pulsed laser set up for second harmonic generation (SHG) experiments. The group performs correlative investigations of 2D materials that they produce themselves, including MoS2.

The Laboratory of Advanced Nanomaterials at Wuhan University has an alpha300 RA Raman/Atomic Force Microscopy system with a 488nm laser, a UHTS300 spectrometer with an EMCCD for detection, a super continuum white light source for photocurrent and photoluminescence measurements and a temperature stage with a range of -196°C to +1000°C. This stage allows the researchers to recreate the conditions of chemical vapor deposition (CVD) growth for optimal multimodal imaging and characterization of 2D materials.

The School of Materials Science and Engineering at Huazhong University of Science and Technology (HUST) operates an alpha300 RAS featuring detection from 350nm to 1700nm with three UHTS spectrometers. The setup is optimized for experiments that employ Raman microscopy, photoluminescence, scanning near-field optical microscopy (SNOM), second harmonic generation (SHG) and time correlated single photon counting (TCSPC) methods such as fluorescence lifetime imaging (FLIM). With their primary focus on 2D materials, the group produced almost 20 peer-reviewed publications in 2018 alone using this versatile and modular instrument.

These examples offer only a glimpse into the range of configurations possible with the alpha300 series. The WITec sales team is ready to discuss your individual requirements and to start configuring the system that is right for you.


An alpha300 RA Raman/Atomic Force Microscopy system for second and third harmonic generation (SHG and THG) investigations of molybdenum disulfide at the same position using a 1560nm picosecond pulsed laser and a temperature stage with a range of -196°C to +1000°C .

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October 2019

Nobel Prize 2019 winner John B. Goodenough uses WITec Raman microscopes for Li-Ion Battery research

This year’s Nobel Prize in Chemistry was awarded to John B. Goodenough, M. Stanley Whittingham and Akira Yoshino "for the development of lithium-ion batteries."

Raman microscopy is a well-established and compelling technique for the characterization of electrochemical materials. John B. Goodenough’s research group at the University of Texas in Austin relies on a WITec alpha300 R for spectroscopic Raman imaging. (

Most recently, the group at the Texas Materials Institute and the Cockrell School of Engineering has published some of their latest findings using Raman Imaging among others to investigate improved electrodes and electrolytes:

Exceptional oxygen evolution reactivities on CaCoO3 and SrCoO3
Xiang Li, Hao Wang, Zhiming Cui, Yutao Li, Sen Xin, Jianshi Zhou, Youwen Long, Changqing Jin and John B. Goodenough
Science Advances 09 Aug 2019: Vol. 5, no. 8
DOI: 10.1126/sciadv.aav6262

Garnet Electrolyte with an Ultralow Interfacial Resistance for Li-Metal Batteries
Yutao Li, Xi Chen, Andrei Dolocan, Zhiming Cui, Sen Xin, Leigang Xue, Henghui Xu, Kyusung Park, and John B. Goodenough
J. Am. Chem. Soc. 2018, 140, 6448−6455

Polar polymer-solvent interaction derived favorable interphase for stable lithium metal batteries
Jiwoong Bae, Yumin Qian, Yutao Li, Xingyi Zhou, John B. Goodenough, Guihua Yu
Energy Environ. Sci., 2019, Advance Article


WITec would like to congratulate John B. Goodenough, M. Stanley Whittingham and Akira Yoshino for winning the 2019 Nobel Prize.

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October 2019

Conference Review: 16th Confocal Raman Imaging Symposium

The international chemical imaging community gathered once again in Ulm, Germany to share and discuss results, methods and technologies related to Raman microscopy. Almost one hundred attendees heard presentations arranged into distinct sessions under the headings: Nanotechnology and Low-dimensional Materials, Geosciences, Life Sciences, Applied Chemical Analysis, and Contributed Talks. Poster sessions provided a relaxed forum for browsing the many scientific results entered into this year’s Poster Award competition and a fascinating evening lecture looked at the entirety of progress in microscopy.

A grand total of seventeen presentations were delivered from the stage of the Ulm Stadthaus’s auditorium. Sebastian Schlücker (University of Duisburg-Essen, Germany) set the conference in motion with his introductory lecture on the theoretical background of Raman spectroscopy, including its classical and quantum mechanical descriptions, and its use in microscopy. An accompanying interactive quiz let the audience test their understanding of the physics behind the Raman effect. Olaf Hollricher (Managing Director-Research and Development, WITec GmbH) then detailed Raman imaging instrumentation, including spectrometers, detectors and software tools, in addition to describing considerations such as resolution and throughput. José Fernández (Instituto de Ceramica y Vidrio, CSIC, Madrid, Spain) then explored the combination of other methods with Raman imaging in his talk on correlative microscopy techniques.

Following the first poster session, it was time for the evening lecture. Charles Lyman, the Chief Editor of Microscopy Today, reviewed the course of innovation in microscopy while providing technological and historical context. He categorized advances as either revolutionary or evolutionary and reserved the term “breakthrough” for those that enabled scientists to see something previously inaccessible and that led to the establishment of a new field of study. This comprehensive account of the development of microscopy closed out the first day of the Symposium.

The second day of the conference began as it should, with coffee, and the fluent multidisciplinary exchange of ideas that the event has become known for. The first session of the day was dedicated to nanotechnology and low-dimensional materials. Yuan Huang (Chinese Academy of Sciences, Beijing, China) presented measurements of molybdenum disulfide and showed how Raman and photoluminescence can be used to monitor their strain-induced properties. Holger Schmalz (University of Bayreuth, Germany) showed how his work on electrospun multicomponent polymer fibers, particles and mesostructured systems benefits from Raman imaging. Nanostructured and composite membranes, Janus fibers and biohybrid microparticles were among the application examples he included in his talk. The session concluded with a presentation from Simon Thiele (Forschungszentrum Jülich and Helmholtz Institute Erlangen-Nürnberg for Renewable Energy, Erlangen, Germany) on serial section-based Raman tomography. The process of compiling 2D Raman scans into 3D images was memorably visualized with slices of marble cake.

Geosciences were the focus of the next session, and two groups showed the audience the depth of the information that can be extracted from mineralogical samples. Maria Alexandrovna Sitnikova and Khulan Berkh (Federal Institute for Geosciences and Natural Resources, Hannover, Germany) offered a view into their research on distinguishing polymorphs using RISE (Raman Imaging and Scanning Electron) microscopy and included an example of 3D Raman imaging’s ability to reveal melted inclusions below a sample surface. Linda Prinsloo (University of the Witwatersrand, Johannesburg, South Africa) presented her work on prehistoric stone tools that provides insight into human technological development. She carefully observes the response of rocks to heat to understand the production processes used to create them. Trace substances such as fatty acids found on the tools also tell us about how our ancestors employed their technology.

The next session featured applications of Raman in the life sciences. Katja Schenke-Layland (University of Tübingen, Germany) began with her investigations of engineered tissues for personalized medicine and monitoring of phenotype switching, including examples of smooth muscle cells for cardiovascular tissue and pseudo-islets expressing insulin trapped on a chip. Peter Vikesland (Virginia Tech, Blacksburg, USA) detailed the method of surface-enhanced Raman scattering (SERS) and described how surface plasmon enhanced elastic scattering signals can be used as internal standards to compensate for the signal heterogeneity of SERS substrates.

Applied chemical analysis was the common thread of the next session and Lars Meyer (BASF SE, Ludwigshafen, Germany) started it off with a medley of analytical tasks that he addresses in his industrial laboratory using Raman imaging. For example, he showed how gypsum crystallization can be monitored and its rate of formation regulated through polymer additives. Erik Emmons (U.S. Army Research Laboratory, Aberdeen, USA) employs Raman microscopy for the analysis of samples relating to chemical, biological and explosives defense. His talk featured results of explosives detection from fingerprints and showed the ability of Raman microscopy to distinguish between viable and deactivated biological spores.

The contributed talks that concluded the second day at the Ulm Stadthaus were dispatches right from the forefront of Raman technology. Patrick Altmann (attocube systems AG, Haar, Germany) presented several examples of cryogenic Raman spectroscopy and imaging in high magnetic fields for research on low-dimensional materials and showed how the Raman spectra of a single graphene flake can be affected by changes in magnetic field strength. Bastian Barton (Fraunhofer Institute for Structural Durability and System Reliability LBF, Darmstadt, Germany) explained how he uses 3D Raman imaging for analyzing multicomponent polymers and the ways in which additives can serve as flame retardants and structural reinforcements. An example he provided was a 3D representation of the core-shell structure of lubricant-containing microcapsules embedded in a polymer matrix. Emil Bjerglund (Danish Technological Institute, Aarhus, Denmark) gave a talk that concerned the detection of document fraud. He showed how forged receipts can be revealed by using Raman spectroscopy to chemically analyze the ink, as its spectra change slightly over time. The non-destructive and label-free nature of the technique is essential for this application. Armin Zankel (Graz University of Technology, Austria) wrapped up the session with a look at the combination of Raman imaging, electron microscopy (RISE) and energy-dispersive X-ray spectroscopy. His example measurements from materials science included vivid depictions of polymers and several mineralogical samples.

As the day turned to evening the attendees reconvened in the historic City Hall of Ulm for the conference dinner and the announcement of the winner of the Poster Award. Locally brewed refreshments and traditional Swabian culinary specialties accompanied discussions of the research presented. The competition between twenty-five scientific posters was intense and many favorites emerged among the guests. The jury had the difficult task of choosing only one and ultimately selected Birgit Bräuer of the University of Vienna as the winner of the 2019 WITec Poster Award. Her submission, Surface Characterization of Escherichia coli-imprinted Polymers using Confocal Raman Microscopy, is a striking demonstration of the utility and versatility of the technique in establishing the presence or absence of bacteria in a sample.

The third day of the Symposium brought the attendees from the city center up to WITec headquarters for demonstrations of the very latest in confocal Raman imaging and correlative microscopy instrumentation. For many, it was their first opportunity to see technologies such as the ParticleScout microparticle analysis tool in action.

The 16th Confocal Raman Imaging Symposium was once again a resounding success, with the variety of application fields represented and the balance between multidisciplinary appeal and scientific depth maintaining the exceptional standard established by previous years.

The 17th Confocal Raman Imaging Symposium will take place from September 28th - 30th, 2020.

Birgit Bräuer, winner of the 2019 WITec Poster Award (left), with WITec’s managing director Joachim Koenen (right) at the award ceremony.
Her poster titled „Surface Characterization of Escherichia coli-imprinted Polymers using Confocal Raman Microscopy“ presents a method for detecting bacteria using Raman microscopy and is available for download.

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